ABSTRACT
Introduction: Patients with acute COVID syndrome have significant cognitive impairment. Although different research had focused on assessing the condition of these patients in the hospital period and in the short term, there are no studies that evaluated these alterations in the long term. The cognitive impairment of long COVID patients may be an important factor for the development of intervention programmes tailored to this population. Objetive: The main objetive of this study was to evaluate the presence of cognitive impairment in long COVID syndrome patients one year after infection. Patients and Methods: In this observational study, long COVID patients were included. These patients were evaluated one year after infection and they were compared to a control group matched by age and gender. Anxiety, depression, memory and concentration problems were measured with items from a comprehensive multi-system telephone screening tool called COVID-19 Yorkshire Rehabilitation Screening (C19-YRS). Result(s): A total of 455 patients and 451 controls were included in this study. Anxiety (p<0,05), depression (p<0,001), memory (p<0,001) and concentration (p<0,001) had shown significant results compared to the control group. Conclusion(s): This study found that long COVID syndrome patients had significant cognitive impairment one year after infection, with increased levels of anxiety, depression and difficulties in concentration and decreased memory. Early interventions for cognitive impairment may improve or prevent further deterioration.
ABSTRACT
Introduction: Although respiratory manifestations are the most common manifestations of COVID-19, the clinical presentations of the disease are very variable including extrapulmonary signs and symptoms. One of the most common extrapulmonary manifestations is pain, which can occur in the acute phase as well as in the short and long term. Identifying the characteristics of this pain will allow the development of treatment programmes tailored to the needs of long COVID patients. Objetive: The main objetive of this study was to identify the pain characteristics in long COVID syndrome patients one year after infection. Patients and Methods: In this observational study, long COVID patients were included. These patients were evaluated one year after infection and they were compared to a control group matched by age and gender. The affective and sensory characteristics of pain was evaluated with McGuill Pain Questionnaire (MPQ). Pain intensity was assessed with the pain intensity subscale of the Brief Pain Inventory (BPI) and pain interference was evaluated with the pain interference subscale of Brief Pain Inventory (BPI) and total score of PROMIS-Pain Interference (PROMIS P-I). Result(s): A total of 455 patients and 451 controls were included in this study. The affective and sensory characteristics (p<0,001), intensity (p<0,001) and interference (p<0,001) of pain showed significant results compared to the control group. Conclusion(s): This study found that long COVID syndrome patients presented poorer affective and sensory characteristics of pain and greater levels of pain intensity and interference.
ABSTRACT
Introduction: Long COVID is a syndrome characterised by persistence of symptoms after acute SARS-CoV-2 infection. Patients with long COVID may present with a wide range of symptoms, including respiratory, cardiovascular, musculoskeletal, neurological, gastrointestinal and other symptoms. These symptoms can lead to a decrease in activity levels and health-related quality of life of patients. Objetive: The main objetive of this study was to evaluate the activity levels and health-related quality of life of long COVID patients one year after infection. Patients and Methods: In this observational study, long COVID patients were included. These patients were evaluated one year after infection and they were compared to a control group of subjects who had successfully recovered from COVID infection without persistent symptoms matched by age and gender. The activity levels of the patients were assessed with the international physical activity questionnaire (IPAQ) and the health-related quality of life was assessed with the EuroQoL 5 dimensions 5 levels (EQ-5D-5L). Result(s): A total of 455 patients and 451 controls were included in this study. The IPAQ (p<0,001) and the five dimensions of EQ-5D-5L (p<0,001) showed significant results compared to the control group. Conclusion(s): This study found that long COVID syndrome patients presented poorer activity levels and health-related quality of life. The development of treatment programmes tailored to their needs will help to prevent the deterioration caused by this syndrome.
ABSTRACT
Introduction: Long-COVID patients are individuals that have ongoing symptoms persisting for weeks to months after SARS-CoV-2 infection. The incidence is increasing and more studies are necessary to deepen the knowledge of these patients. Objective(s): To investigate the clinical profile, symptomatology and sequelae of long-COVID patients. Method(s): In this observational study, long-COVID patients were included and evaluated by an internet survey. Sociodemographic data were obtained from the patient together with the COVID-19 Yorkshire Rehabilitation Screening Tool (C19-YRS). Consent of the patient was sought at the beginning of the survey. Result(s): Finally, 89 patients were included in the study. The main age was 43,34 +/-7,85 years, they were overweight, and non-smokers (84%), the 85,4% were females and the median time of infection was 8,18 +/-3,93 months. The results have shown significant impairments in dyspnea at rest or under exercise, personal care, pain, fatigue, psychological distress, and quality of life after COVID infection. Additionally, patients have referred sensitivity of the throat, voice and swallowing impairment, gastrointestinal disorders, and attention and memory problems. Conclusion(s): Patients with long- COVID present multiple sequelae that affect their health status, being necessary more future studies.
ABSTRACT
Background: The COVID-19 pandemic impacts on general population, although patients with COPD have been affected to a greater extent due to their previous condition of disability. Recent studies indicate that pain is a significant symptom in COPD patients with an estimated prevalence of 32-60%. Objective(s): The objective of this study was to analyze the pain perception variables in COPD patients across the COVID-19 pandemic. Method(s): In this cross-sectional study, stable COPD patients without a COVID-19 diagnosis were evaluated before and during the pandemic. The main outcomes were the pain perception (general pain sensitivity, pain intensity, pain interference, and pressure pain sensitivity) and the psychological vulnerability (overall health status, anxiety, and depression). Result(s): The descriptive data of participants showed no significant differences between COPD patients before the pandemic and COPD patients during the pandemic. COPD patients experienced an enhanced pain perception, highlighted with statistical differences in general pain sensitivity, pain intensity, and pain interference (p<0.05) during the COVID-19 pandemic. Furthermore, the overall perceived health status of COPD patients during the pandemic was significantly lower than before the pandemic (p<0.05). Conclusion(s): We concluded that COPD patients during the COVID-19 pandemic presented an increase in pain perception accompanied by the enhanced psychological vulnerability.